Why We Use Non-Adjuvanted Vaccines for Cats

Most cat owners never hear the word adjuvant, and there is no reason they should have to. But it is the reason we buy the feline vaccines we buy at Heights Hospital for Animals in Yorktown Heights, NY, and it is worth understanding if you have a cat.
What Is An Adjuvant?
An adjuvant is an additive mixed into some vaccines to provoke a stronger immune response. It works by creating deliberate local inflammation at the injection site, which draws immune cells to the area and teaches the body to respond to the vaccine. It is an old and effective piece of vaccine design, and for most species it is unremarkable.
Why It Matters More For Cats Than For Dogs
Cats are unusual. In a small number of cats, a site of persistent inflammation can eventually become the origin of an aggressive tumor called a feline injection-site sarcoma. Dogs do not do this. The connection was first noticed in the early 1990s, and it changed how the veterinary profession vaccinates cats.
Two things are worth saying clearly:
- It is rare. Commonly cited estimates put injection-site sarcomas somewhere between 1 in 10,000 and 1 in 30,000 vaccinated cats.
- It is not a reason to skip vaccines. Panleukopenia and rabies kill cats. Rabies is also fatal to humans and is required by New York state law. The diseases these vaccines prevent are a far larger risk to your cat than the vaccine is.
The reasonable response is not to vaccinate less. It is to remove the variable you can remove.
What We Carry
We use non-adjuvanted feline vaccines. Without the adjuvant, the vaccine relies on a different design to generate immunity, and it does not leave the same persistent inflammatory reaction behind. Protection is what we expect it to be, and one known contributor to injection-site reactions is off the table.
Where We Give The Injection
Just as important as which vaccine we use is where it goes. We give feline vaccines low on a limb, below the elbow on a front leg or below the knee on a back leg. We do not vaccinate cats between the shoulder blades or in the scruff, which is where the profession used to put them.
The reason is straightforward. A lump low on a leg is easy to find, easy to measure, and easy to watch. And in the rare case that a lump does turn out to be something, a site that far down the limb can be removed completely. A tumor in the middle of a cat's back cannot, which is exactly why feline guidelines moved away from that spot.
This costs nothing and changes nothing about your cat's visit. It is simply where the needle goes.
The Lump Rule To Know At Home
A small, soft swelling at an injection site in the days after a vaccine is common and usually resolves on its own. What matters is whether it behaves itself. Feline specialists teach a simple rule, sometimes called 3-2-1. Have a lump checked if it is:
- Still there 3 months after the vaccination
- Larger than 2 centimeters across, roughly the width of a fingertip
- Still growing 1 month after the vaccination
Any one of those three is a reason to call us. Nearly always it turns out to be nothing. On the rare occasion it is not, early is dramatically better than late with these tumors.
What This Looks Like At Your Cat's Visit
Nothing about your appointment changes. You will not be asked to choose a vaccine line or pay extra for it. It is simply what we stock, alongside the rest of how we set up feline visits: a separate cat entrance, a cat-only waiting room and exam room, and calming pheromones so the vaccine is the least stressful part of the day.
If you want the full list of what each feline vaccine protects against, our pet vaccinations page covers it. And if your cat is behind on vaccines because the last visit went badly, tell us when you schedule and we will plan around it.
Questions about your cat's vaccines are always welcome. Schedule an appointment or call us at (914) 962-5579.


